Most likely Republican nominee in 2024 (November 2017)

[Pennsylvania Deplorable]

If Trump wins in 2020 (or if he decides not to run for reelection) Pence is the natural favorite. Being Trump's VP makes him acceptable to the Trump base, his experience in Washington makes him establishment approved, and his social conservatism is popular with evangelicals who voted for Cruz. He's the ultimate generic republican.

Other notes: Despite this site's weird obsession with her, Nikki Haley will never be a major national republican. She picked the wrong side of the culture war when she tore down the confederate flag and doubled down on attacking Trump even after the primaries were over. Tom Cotton on the other hand is a rising star. He's strong on immigration. Even if it doesn't pass, a national debate on the RAISE Act (the first real attempt to overhaul legal immigration since Hart Cellar in 1965) would propel him into the spotlight. While he has a conservative voting record, he isn't prone to antics like Cruz's government shutdown, hasn't really made any gaffes that I know of, and it doesn't hurt that he's a veteran. I expect him to run eventually and I also expect Cruz and Rubio to run again. The GOP built up a lot of young talent during the Obama years and democrats desperately need to do likewise now (midterms traditionally favor the party not in the white House).