False, because "ever" is a long time.
A more interesting question is "will a Republican win Cali in our lifetimes?" That is a fair bit more ambiguous. I think there'll probably be a mega landslide where Cali jumps on for the ride in the distant future, but it'll be tricky to see it voting to the right of the nation under most plausible coalitions.
Agreed, but, an even more interesting question is: "Will CA vote to the right of the nation in our lifetimes". Assuming average life expectancy, the average Atlas poster might live on until...2070?