I mean, it will obviously be this because 2016 was a one-time thing, a "populist" like Sanders (who wins the Democratic nomination without any trouble whatsoever) could clearly do well in WV/KY/MO/AR/etc. (all of which are populist Democratic states at heart), VA and CO will "come home" for the GOP once Trump is gone, Schumer's Better Deal slogan, etc.
In all seriousness, though: I expect to see something like this by 2030...
This map isn't necessarily the result of a "complex realignment" but rather remarkably little change.
And in 2040: