Obama lost the state by 17 points in 2012, so this is about on par with that.
Yes, and he did better there in 2012 than in 2008, suggesting it was all about black turnout. I would be shocked if Louisiana didn't trend R in PVI this year. This is consistent with a loss between Romney and McCain levels nationally for Trump, but I don't think it's consistent with a 13 point loss.
Louisiana, Arkansas, Tennessee, Kentucky, and West Virginia should all trend R this year. I'd think Missouri would too, but some polling has me less confident here. Appalachian/Upland/Gulf Coast whites are just up Trump's alley.