Conservative Republicans were generally isolationist on foreign policy and more open to New Deal measures that were good for urban areas, but not so much for rural areas.
Dixiecrats were unabashed hawks and tended to be hostile to New Deal measures that were good for urban areas, but very open to ones that modernized rural areas that had pretty much no electricity up to that point.
The Dixiecrats being hawks when it came to WWII is ironic considering who's been in the news for defending the Robert E. Lee statue. By the way, what states did the isolationists tend to come from?
Not ironic at the time. Many of them still rang badly from stories about the Civil War and saw themselves as avengers.