Depending upon your definition of the Bootheel, Poplar Bluff isn't the largest town in Southeast Missouri: among cities in the 8th District, it falls behind Cape Girardeau and Rolla, respectively, according to the 2010 Census; 2013 estimates show that it has fallen to fourth place now behind Farmington. Just throwing that out there
I don't consider Cape or Rolla in the Bootheel, but I guess it could be quibbled over.
Yeah, as someone who lives near Cape, I don't personally feel like I'm in the Bootheel until after Scott City.