Of course Hillary Clinton will inevitably win.
Just ask President Dewey.
Of course Chuck Schumer and James Lankford will inevitably win. Just ask President Dewey.
Seriously though, if you just want to apply the extremely lame "nobody ever knows what will happen!!!11!1!!1!11!" thing to every election, why bother discussing politics at all?
The difference is that polling 2 years ago in an open-seat general election is almost invariably wrong, whereas OK/NY senatorial predictions are not.
Hillary is most likely the next President, but hardly a shoe-in.