I think this may just be an oddity of low Republican turnout and an unusually strong Democratic opponent. He may make Issa sweat a little, but shouldn't be a problem winning.
Worth noting that the other OC Republicans didn't have as much trouble.
Ed Royce has a decent opponent and a similar PVI district, and he crushed the primary with 60%+.
His district is more San Diego County than Orange, isn't it? Anyway, doesn't matter, if he's winning with 51% now he could win that way in November and the only surprise would be how close it is.