Patrick Murphy has the right profile to run statewide, representing a district that is somewhat more Republican than the state as a whole is not a bad staging point for a statewide campaign.
The mayor of Jacksonville might be an option (depending on how good a job he's done as mayor), as well as Val Demings.
Alvin Brown could never win the Democratic primary; he's far too right wing for the urban leftists. It'll get him a pretty easy reelection, but he'll never fly with the state Dems unless they're even more desperate than normal (which is already pretty desperate).
He's to the left of Charlie Crist, so the urban leftists can learn to deal with it if the DSCC clears the way.