It is more about having a "Southern Candidate" on the ticket. So far, Biden is the closest to a southern candidate.
Apparently Romney thinks he can keep Virginia and Florida with Ryan.
The country loves "southerners" and the "southern strategy" proved effective for JFk, LBJ, Nixon, Carter, Reagan, CLinton, and Dubya.
Its more important to have a "cultural Southern" on the ticket who cares about conservative Social values, than a specific religious label. Catholic Santorum would have won the Southern states.
Every presidential candidate has some type of Southern strategy. The only two Southerners to ever run on the Republican ticket were both Bushes. And as for Americans loving Southerners, I disagree. Southerners are still portrayed by the media as stupid, racist, lazy, and unsophisticated. While this is wrong and untrue, it's sill the perception that many people have.