If George W. Bush lost the 2004 election by narrowly failing to carry OH, do you think there would have been a real push to amend the constitution and abolish the EC? If only ~200k votes on OH shift, Kerry wins with 272 EVs while still losing the NPV to Bush by more than Bush himself lost to Gore.
With the EC twice producing a vote loser as prez in a row and with both parties going through the same frustration, I think there could have been a real chance for reform. Was possibly the best shot we ever had to end the EC and elect the POTUS by popular vote.
State level changes probably, like EVs being allocated proportionally or via Congressional District.