So from now on, you have to control the senate to get any high level judicial nominees confirmed at all?
No, the Democrats will bend over backwards for the next Republican President, again.
The next time we have a Republican president, there won't be enough Dem senators in states he/she won to matter anymore. From 2000-2008 you had Dem senators in 60% Bush states, so it's 100% understandable that they were less partisan than Republicans currently are. This goes both ways. If a Democrat gets 60% in CO and NV in 2020, you can bet Gardner and Heller will vote for 2/3rds of his/her nominees.