I've all always thoughtvit would be easier to target mountain and plaims states -/Montana, the Dakotas, Alaska etc. They have an over sized influence on congress, a fairly populiat tradition, less black/white polarisation and I assume TV advertising is cheaper than in coastal areas.
This is just my personal anecdotal observations as someone with relatives and friends throughout the region in question, but.... I think targeting the Mountains and Plains states would be very difficult if not impossible in the near future. Years and years of FOX News and its ilk, plus the much-disliked Obama, have led to strong hostility to the national Democratic brand. Local Democrats can and do win, but "Washington D.C." is viewed as evil, making winning electoral votes in those states extremely difficult.