Bibi will likely want to annex Area C, which amounts more than 60% of the territory including all settlements. The bulk of the Palestinian population is located in Areas A and B, which will remain as encircled ghettos or, using Kafka's terminology, penal colonies. This is an obvious criminal design.
Splitting up Palestinians up - into over thirty main pieces and hundreds more of tiny enclaves - is not a two state solution. It is doing to the Palestinians what the “moderate, good Nazis” wanted to do with the Jews - keeping them in closed off neighborhoods, allowing no outside interaction or economic development. Netanyahu’s real slogan should be Permanent Poverty for Palestine.
Only if the Palestinians were barred from entering Israel at all; which would be unlikely, as someone is still going to be needed to collect the trash. Also, apartheid in South Africa involved segregation in public transport, toilet facilities etc. That's rather impossible to enforce in an area where Mitzrahim Jews and Palestinians look very much like each other.