I saw reporting (cant remember where) that even Team Biden see that Hillary is already too well organized in IA and they are eyeing SC as his best chance for a first win, presumably he thinks he can peel off African Americans support due to his connection to Obama, but will they go for him if he is 0 for 2 after IA and NH?
This obviously isn't a very close comparison, but Gingrich won SC by 13 points after coming in 4th in Iowa and 5th in New Hampshire. All it really takes is a change in media narrative and "Hillary was underwhelming in Iowa and Sanders was underwhelming in New Hampshire" might just do the trick for him.