At only 45 years old, I don't see why Charles Djou wouldn't take another shot at this seat.
Well he's now lost three consecutive general elections for this seat (2010, 2012, and 2014), and the 2014 race was during a giant Republican wave and the incumbent wasn't running for reelection. Hanabusa, despite not currently holding the seat, is probably still better known than Takai, and would defeat Djou easily in a presidential year. It would be dumb for him to run, I think he needs to take a break from running for office for awhile and maybe make a return to politics later on by running for governor or something (some office less partisan than congress or senate).