At least two virtually certain ones that every current member of the Court on the right has expressed support for -- prohibiting affirmative action (possibly up to criminal penalties if Thomas has his way with it) and reviving the nondelegation doctrine (to some extent, though probably not in a retroactive way, but maybe if Thomas has his way with it) -- remain outstanding, both of which would basically revolutionize the American body politic. The former is also an overwhelmingly popular issue for the GOP (more so than
Roe for Democrats; banning affirmative action is a 50-state PV winner, though probably not DC); the latter is an inside-the-weeds enough thing that most people would have no opinion, much as with
Citizens United, but it probably constitute the largest change to how the government works this side of the New Deal.